Structural Principles Analysis of Host-Pathogen Protein-Protein Interactions: A Structural Bioinformatics Survey

a structural survey of the polish posters

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Structural Models for Host-Pathogen Protein-Protein Interactions: Assessing Coverage and Bias

Recently, we applied structural systems biology to host-pathogen interaction and constructed the human-virus structural interaction network (SIN) based on a combination of solved structures and homology models. Subsequent analysis of the human-virus SIN revealed significant differences between antagonistic human-virus and cooperative within-human protein-protein interactions (PPIs). Although th...

Structural Bioinformatics for Protein Engineering

Protein-RNA interactions: a structural analysis.

A detailed computational analysis of 32 protein-RNA complexes is presented. A number of physical and chemical properties of the intermolecular interfaces are calculated and compared with those observed in protein-double-stranded DNA and protein-single-stranded DNA complexes. The interface properties of the protein-RNA complexes reveal the diverse nature of the binding sites. van der Waals conta...

Rabies Infection: An Overview of Lyssavirus-Host Protein Interactions

Viruses are obligatory intracellular parasites that use cell proteins to take the control of the cell functions in order to accomplish their life cycle. Studying the viral-host interactions would increase our knowledge of the viral biology and mechanisms of pathogenesis. Studies on pathogenesis mechanisms of lyssaviruses, which are the causative agents of rabies, have revealed some important ho...